Exactly about Gene Transfer and Genetic Recombination in Bacteria

Exactly about Gene Transfer and Genetic Recombination in Bacteria

The following points highlight the 3 modes of gene transfer and recombination that is genetic germs. The modes are: 1. Transformation 2. Transduction 3. Bacterial Conjugation.

Mode no. 1. Change:

Historically, the development of change in germs preceded one other two modes of gene transfer. The experiments carried out by Frederick Griffith in 1928 suggested for the very first time that a gene-controlled character, viz. Formation of capsule in pneumococci, might be used in a variety that is non­-capsulated of germs. The transformation experiments with pneumococci fundamentally generated a similarly significant finding that genes are constructed with DNA.

Within these experiments, Griffith utilized two strains of pneumococci (Streptococcus pneumoniae): one by having a polysaccharide capsule creating ‘smooth’ colonies (S-type) on agar dishes that was pathogenic. One other stress had been without capsule creating ‘rough’ colonies (R-type) and had been non-pathogenic.

Once the capsulated living bacteria (S-bacteria) had been inserted into experimental pets, like laboratory mice, a significant percentage regarding the mice passed away of pneumonia and live S-bacteria could be separated from the autopsied pets.Read more